Effect of immunization against rabies on γ-aminobutyric metabolism in the animal brain
Biochemistry and Biophysics
Received:
- 12 Downloads
Abstract
Subcutaneous injection of fixed rabies virus into albino rats weighing 100–120 g is followed by a decrease in theγ-aminobytyric acid (GABA) concentration in the animals' brains. An increase in the activity of GABA-α-ketoglutarate transaminase also is observed in the brain tissue of animals vaccinated against rabies.
Key words
rabies γ-aminobutyric acid (GABA) immunizationLiterature Cited
- 1.E. L. Avenirova, M. N. Maslova, V. I. Rozengard, et al., Vopr. Med. Khimii, No. 6, 633 (1966).Google Scholar
- 2.T. M. Khizhnyakova, M. Sh. Promyslov, and L. P. Gorshunova, Vopr. Med. Khimii, No. 6, 561 (1974).Google Scholar
- 3.M. Sh. Promyslov, T. V. Solov'eva, and R. I. Aniskina, Vopr. Med. Khimii, No. 6, 619 (1968).Google Scholar
- 4.T. S. Paskhina, Biokhimiya, No. 6, 702 (1954).Google Scholar
- 5.N. N. Yakovlev, Ukr. Biokhim. Zh., No. 2, 175 (1963).Google Scholar
- 6.C. F. Baxter and E. Roberts, J. Biol. Chem.,236, 3287 (1961).Google Scholar
- 7.E. Flory, Naturwissenschaften,40, 295 (1953).Google Scholar
- 8.S. Saito and Y. Tokunaga, J. Pharmacol. Exp. Ther.,157, 546 (1967).Google Scholar
- 9.E. Roberts, Inhibition in the Nervous System and γ-Aminobutyric Acid, US Air Force Office of Scientific Research, Proceedings of International Symposium, Oxford (1960), p. 144.Google Scholar
Copyright information
© Plenum Publishing Corporation 1976