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Bulletin of Experimental Biology and Medicine

, Volume 50, Issue 5, pp 1158–1162 | Cite as

The use of an experimental model of hypertonia for assessing the efficiency of schizandra Chinensis in atherosclerosis

  • Z. M. Volynskii
  • M. K. Mikushkin
Pharmacology
  • 17 Downloads

Summary

Experiments with 28 rabbits have shown that seeds ofSchizandra chinensis administered in a dose of 0.2 g/kg for experimentally induced atherosclerosis will reduce the cholesterol level in the blood and decrease or totally prevent atherosclerosis of the aorta and of the coronaries in the normotonic rabbits. The same doses of S. chinensis administered to hypertensive rabbits fail to exert any effect. In the search for effective agents for prophylaxis and treatment of atherosclerosis it is necessary to test them not only on models of experimental atherosclerosis, but likewise on models of atherosclerosis associated with hypertension.

Keywords

Public Health Hypertension Cholesterol Atherosclerosis Experimental Model 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau Enterprises, Inc. 1961

Authors and Affiliations

  • Z. M. Volynskii
    • 1
  • M. K. Mikushkin
    • 1
  1. 1.Department No. 2 of Hospital Therapy of the S. M. Kirov Order of Lenin Academy of Military MedicineLeningrad

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