Bulletin of Experimental Biology and Medicine

, Volume 56, Issue 6, pp 1315–1318 | Cite as

Effect of the electrical polarization of motor nerve endings and their ability to conduct rhythmic impulses

  • I. A. Vladimirova


A study was made of the effect produced by electric polarization of the motor nerve endings on the conduction of the rhythmic impulses through them. Increased rhythmic end-plate potentials from the hyperpolarized endings were subject to a lesser summation than in normal conditions and weakened more rapidly following prolonged rhythmic stimulation. Hyperpolarization of the nerve endings removed the presynaptic block caused by an increased potassium content in the solution surrounding the muscle. Depolarization of the nerve endings promoted the development of presynaptic blocking. These changes were observed only in local polarization of synaptic plates. A hypothesis is put forward on the nature of the changes occurring in the presynaptic endings, leading to the changes of efficacy of their transsynaptic action and to presynaptic blocking.


Public Health Potassium Normal Condition Nerve Ending Motor Nerve 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1964

Authors and Affiliations

  • I. A. Vladimirova
    • 1
  1. 1.Laboratory of General PhysiologyA. A. Bogomolets Institute of Physiology of the AN UkrSSRKiev

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