Phthalazine and related heterocycles
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3-Aryl- and 3-alkyl-4-phthalazone-1-carboxylic acids are formed by the reaction of the corresponding mono-substituted hydrazines and phthalic acid, but higher yields of 3-alkyl-4-phthalazone-1-carboxylic acids are obtained by the alkylation of 4(3H)-phthalazone-1-carboxylic acid or its esters. The acids obtained have been characterized by their UV spectra and have been converted into methyl esters and amides (via the chlorides).
KeywordsMethyl Chloride Ester Organic Chemistry Amide
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