Pharmaceutical Chemistry Journal

, Volume 1, Issue 1, pp 2–4 | Cite as

Indole derivatives

XXXII. Indolylalkyl mercaptans and some of their derivatives
  • N. N. Suvorov
  • V. N. Buyanov


The reaction ofω-(indolyl-3)-alkyl bromides with sodium thiosulfate gave Bunte salts (sodium indolylalkyl thiosulfates) which were converted into disulfides by the action of alkali. These were reduced with lithium aluminum hydride to mercaptans which then were converted by the action of methyl iodide into sulfides and these into sulfonium salts. A chemotherapeutic investigation showed the Bunte salts to have weak tuberculo static activity.


Sulfonium Sulfide Lithium Bromide Iodide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    F. P. Doyle, W. Ferrier, D. O. Holland, et al., J. Chem. Soc., 2853 (1956).Google Scholar
  2. 2.
    Vitali and Messini, Boll. Sci. Fac. Chim. Ind. Bologna,17, 84 (1959); C. A.,54, 19644 (1960).Google Scholar
  3. 3.
    Toshio Hoshino and Kenya Shimodaire, Bull. Chem. Soc. Japan,11, 221 (1936); C. A.,30, 5982 (1936).Google Scholar
  4. 4.
    F. Lingens and K. Weiler, Lieb. Ann.,662, 139 (1963).Google Scholar

Copyright information

© Consultants Bureau 1968

Authors and Affiliations

  • N. N. Suvorov
    • 1
  • V. N. Buyanov
    • 1
  1. 1.D. I. Mendeleev Moscow Chemicotechnological InstituteUSSR

Personalised recommendations