Rat hepatocytes in single cell suspension: A still suitable system for lipid peroxidation studies
Session 1 Hepatic Cell Cultures Invited Lectures
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Abstract
The investigation of toxic compounds which need a previous metabolic activation often gets advantage by the employment of cell suspensions, in most of the cases rat hepatocytes. In particular, this model system allows the characterization of lipid peroxidation kinetics, the evaluation of its pathogenetic role in the induction of cell death and the analysis of the interaction among different prooxidant compounds in bringing about both oxidative damage and cytolysis.
Keywords
Lipid Cell Death Lipid Peroxidation Cell Suspension Single Cell
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© Kluwer Academic Publishers 1993