Cellular and Molecular Neurobiology

, Volume 12, Issue 5, pp 463–472 | Cite as

Glial localization of interleukin-1α in invertebrate ganglia

  • Liesbet R. Paemen
  • Eliane Porchet-Hennere
  • Maryse Masson
  • Michael K. Leung
  • Thomas K. HughesJr.
  • George B. Stefano
Article

Summary

  1. 1.

    Mytilus pedal ganglion contains a small population of glial cells that are immunopositive for interleukin-1α. Positively stained fibers can also be seen in the neuropil of these sections.

     
  2. 2.

    The marine wormNereis diversicolor also exhibits positive neural immunostaining for interleukin-1α.

     
  3. 3.

    Both organisms contain hemocytes that contain immunoactivity for interleukin-1α. The study suggests interleukin-1α to be an ancient cytokine given its presence in organisms that evolved significantly earlier than mammals.

     

Key words

interleukin-1α invertebrates ganglia glia 

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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • Liesbet R. Paemen
    • 1
  • Eliane Porchet-Hennere
    • 2
  • Maryse Masson
    • 2
  • Michael K. Leung
    • 1
  • Thomas K. HughesJr.
    • 3
  • George B. Stefano
    • 1
  1. 1.Multidisciplinary Center for the Study of Aging and Old Westbury Neuroscience InstituteState University of New York at Old WestburyOld WestburyUSA
  2. 2.Laboratoire de Biologie animaleUniversity of Science and Technology of Lille Flanders ArtoisVilleneuve D'AscoFrance
  3. 3.Department of MicrobiologyUniversity of Texas Medical BranchGalvestonUSA

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