Acta Neuropathologica

, Volume 59, Issue 3, pp 237–239

Carbonic anhydrase-III immunohistochemical localization in human skeletal muscle

  • K. Shima
  • K. Tashiro
  • N. Hibi
  • Y. Tsukada
  • H. Hirai
Short Original Communications

Summary

Using the indirect immunoperoxidase method, we studied the localization of carbonic anhydrase-III (CA-III) in frozen sections of biopsies of human skeletal muscle which had no definite pathology. CA-III was found to be localized in Type-I muscle fibers when compared with serial sections stained with myosin ATPase and other reactions. Our finding was in accordance with the biochemical data so far reported. It was thought that CA-III could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases.

Key words

Carbonic anhydrase Skeletal muscle Immunoperoxidase method 

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References

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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • K. Shima
    • 1
    • 2
  • K. Tashiro
    • 1
  • N. Hibi
    • 2
  • Y. Tsukada
    • 2
  • H. Hirai
    • 2
  1. 1.Section of Neurology, Dept. of NeurosurgeryHokkaido University School of MedicineSapporoJapan
  2. 2.First Dept. of BiochemistryHokkaido University School of MedicineSapporoJapan

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