Journal of comparative physiology

, Volume 91, Issue 4, pp 363–375 | Cite as

Manipulation of frequency analysis in the cochlear ganglion of the guinea pig

  • Donald Robertson
  • Geoffrey A. Manley


  1. 1.

    Recordings of extracellular activity were obtained from single cells in the spiral ganglion of the basal turn of the guinea pig cochlea.

  2. 2.

    The spatial distribution of characteristic frequencies of cells in the ganglion was consistent with published data on the location of displacement maxima on the basilar membrane.

  3. 3.

    Large variations in the sharpness of single cell tuning curves were seen between animals. These variations were closely linked to sensitivity differences.

  4. 4.

    The tuning curves of single cells could be made less sharp by slowing the rate of artificial ventilation. These tuning curve changes were reversible and intimately associated with alterations in sensitivity and spontaneous activity.

  5. 5.

    The data point either to the presence of a mechanical non-linearity, or a physiologically vulnerable second filter, as the explanation for the sharpness of neural tuning curves in cochlear nerve fibres.



Single Cell Spontaneous Activity Displacement Maximum Basilar Membrane Curve Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. DeBoer, E.: Initiation of nerve impulses in the inner ear. Proc. kon. ned. Akad. Wet72, 129–151 (1969)Google Scholar
  2. Evans, E. F.: Narrow tuning of the responses of the cochlear nerve fibres emanating from the exposed hasilar membrane. J. Physiol. (Lond.)208, 75–76 P (1970)Google Scholar
  3. Evans, E. F.: The frequency response and other properties of single fibres in the guinea pig cochlear nerve. J. Physiol. (Lond.)226, 263–287 (1972)Google Scholar
  4. Prank, K., Becker, M. C.: Microelectrodes for recording and stimulation. In: Physical techniques in biological research, vol. 5 (Nastuk, W. L., ed.). New York: Acad. Press 1964Google Scholar
  5. Johnstone, B. M., Taylor, K. J., Boyle, A. J.: Mechanics of the guinea pig cochlea. J. acoust. Soc. Amer.47, 504–509 (1970)Google Scholar
  6. Johnstone, B. M., Yates, G.: Basilar membrane tuning. Proc. 85th Meeting Acoust. Soc. Amer. (1973)Google Scholar
  7. Kiang, N. Y. S.: Discharge patterns of single fibres in the cat's auditory nerve. Cambridge (Mass.): M.I.T. Press 1965Google Scholar
  8. Kiang, N. Y. S., Moxon, E. C., Levine, R. A.: Auditory nerve activity in cats with normal and abnormal cochleas. In: Sensorineural Hearing Loss, p. 241–273 (Wolstenholme, G., Knight, K., Eds.) London: Churchill 1970Google Scholar
  9. Moller, A. R.: Studies of the damped oscillatory response of the auditory frequency analyzer. Acta physiol. scand.78, 299–314 (1970)Google Scholar
  10. Nomoto, M., Suga, N., Katsuki, Y.: Discharge patterns and inhibition of primary auditory nerve fibres in the monkey. J. Neurophysiol.27, 768–787 (1964)Google Scholar
  11. Rhode, W. S.: Observations of the vibration of the basilar membrane of squirrel monkeys using the Mössbauer technique. J. acoust. Soc. Amer.49, 1218–1231 (1971)Google Scholar
  12. Smoorenburg, G. F.: Combination tones and their origin. J. acoust. Soc. Amer.52, 615–632 (1972)Google Scholar
  13. Tonndorf, J.: Time/frequency analysis along the partition of cochlear models. J. acoust. Soe. Amer.34, 1337–1350 (1962)Google Scholar
  14. Wilson, J. P., Johnstone, J. R.: Capacitive probe measures of basilar membrane vibration. Symp. on Hearing Theory, LPO Eindhoven (1972)Google Scholar

Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • Donald Robertson
    • 1
  • Geoffrey A. Manley
    • 1
  1. 1.Department of BiologyMcGill UniversityMontrealCanada

Personalised recommendations