Journal of Comparative Physiology B

, Volume 158, Issue 6, pp 771–777 | Cite as

Evidence for glycolytic enzyme binding during anaerobiosis of the foot muscle ofPatella caerulea (L.)

  • A. Lazou
  • B. Michaelidis
  • Is. Beis


The effect of anaerobiosis and aerobic recovery on the degree of binding of glycolytic enzymes to the particulate fraction of the cell was studied in the foot muscle of the marine molluscP. caerulea, in order to assess the role of glycolytic enzyme binding in the metabolic transition between aerobic and anoxic states. Short periods of anoxia (2 h, 4 h) resulted in an increase in enzyme binding in association with the increased glycolytic rate observed; this was particularly pronounced for phosphorylase, phosphofructokinase, aldolase, pyruvate kinase and lactate dehydrogenase. Decreased enzyme binding was observed after prolonged periods of anoxia. These effects were reversed and control values re-established when animals were returned to aerobic conditions. The results suggest that glycolytic rate could be regulated by changes in the distribution of glycolytic enzymes between free and bound forms inP. caerulea foot muscle. This reversible interaction of glycolytic enzymes with structural proteins may constitute an additional mechanism for metabolic control.


Lactate Pyruvate Human Physiology Lactate Dehydrogenase Aerobic Condition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • A. Lazou
    • 1
  • B. Michaelidis
    • 1
  • Is. Beis
    • 1
  1. 1.Laboratory of Animal Physiology, Science SchoolUniversity of ThessalonikiThessalonikiGreece

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