Neuronal loss in the basal nucleus of Meynert in a patient with olivopontocerebellar atrophy
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- Tagliavini, F. & Pilleri, G. Acta Neuropathol (1985) 66: 127. doi:10.1007/BF00688687
A morphometric study of the basal nucleus of Meynert has been performed in a case of familial olivopontocerebellar atrophy with mental deterioration. The magnocellular population of the basal nucleus found to be substantially reduced in number (over 60%) as compared with that of three agematched controls. This finding has not been reported previously and might represent one of the antomic substrates of some of the cognitive disturbances exhibited by a considerable number of patients with olivopontocerebellar atrophy (OPCA).
Key wordsOlivopontocerebellar atrophy (OPCA) Subcortical dementia Basal nucleus of Meynert (bn. M) Neuropathology
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