Acta Neuropathologica

, Volume 77, Issue 6, pp 659–663 | Cite as

Acute autonomic and sensory neuropathy: report of an autopsy case

  • H. Tohgi
  • M. Sano
  • K. Sasaki
  • H. Suzuki
  • T. Sato
  • T. Iwasaki
  • R. Satodate
Case Reports
Received:
Revised:
Accepted:

Summary

A 46-year-old woman presented acute sensori-motor neuropathy of the Guillain-Barré type, followed by a protracted course of profound autonomic and sensory dysfunction. Tests of autonomic functions showed denervation hypersensitivity. Neuropathologically, the trigeminal sensory nuclei, solitary nucleus, the dorsal columns of the spinal cord and dorsal spinal roots showed severe degeneration. Degeneration was found both in the preganglionic (intermediolateral cell columns of the spinal cord) and postganglionic (sympathetic ganglion and celiac ganglion) neurons of the sympathetic nervous system, and the preganglionic (dorsal motor nucleus of the vagus) and postganglionic (Auerbach's plexus) neurons of the parasympathetic nervous system.

Key words

Acute pandysautonomia Autonomic neuropathy Acute polyradiculoneuritis Guillain-Barré syndrome 
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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • H. Tohgi
    • 1
  • M. Sano
    • 1
  • K. Sasaki
    • 1
  • H. Suzuki
    • 2
  • T. Sato
    • 2
  • T. Iwasaki
    • 2
  • R. Satodate
    • 2
  1. 1.Department of NeurologyIwate Medical UniversityMorioka, IwateJapan
  2. 2.Department of PathologyIwate Medical UniversityMorioka, IwateJapan

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