Acta Neuropathologica

, Volume 22, Issue 1, pp 79–87

Recurrent acute necrotizing hemorrhagic encephalopathy

  • Jacques B. Lamarche
  • Peter O. Behan
  • Jose M. Segarra
  • Robert G. Feldman
Original Investigations

DOI: 10.1007/BF00687552

Cite this article as:
Lamarche, J.B., Behan, P.O., Segarra, J.M. et al. Acta Neuropathol (1972) 22: 79. doi:10.1007/BF00687552

Summary

A case of acute necrotizing hemorrhagic encephalopathy which surviced one year following cerebral decompression was studied. This patient was found to have cell mediated hypersensitivity to an encephalitogenic myelin basic protein. The unusual clinical features suggested a diagnosis of multiple sclerosis. The pathological findings revealed that the disease had occurred in bouts and suggested that this illness may have a polyphasic rather than a monophasic course, if the patient survives.

Key words

Acute Necrotizing Hemorrhagic Encephalopathy Acute Hemorrhagic Leukoencephalitis Lymphoblastic Transformation Encephalitogenic Myelin Basic Protein Acute Disseminated Encephalomyelitis Emperipolesis Delayed Hypersensitivity 

Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • Jacques B. Lamarche
    • 1
    • 2
  • Peter O. Behan
    • 1
    • 2
  • Jose M. Segarra
    • 1
    • 2
  • Robert G. Feldman
    • 1
    • 2
  1. 1.Department of NeurologyBoston University School of MedicineBoston
  2. 2.Veterans Administration HospitalBostonUSA

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