Acta Neuropathologica

, Volume 34, Issue 2, pp 171–174 | Cite as

SV 40 related Papova-viruses in human meningiomas

  • A. F. Weiss
  • K. D. Zang
  • G. D. Birkmayer
  • F. Miller
Short Original Communications


Human meningiomas show characteristic chromosome aberrations very similar to those reported in human cell cultures experimentally transformed by Simian virus 40 (SV 40). Three out of eight meningiomas tested showed SV 40 specific tumor antigen but no virus capsid antigen. Experiments to rescue virus were successfully performed. Electron microscopic studies of these cell cultures revealed cytoplasmic inclusions containing virus particles which corresponded in size and morphology to Papova viruses.

Key words

Brain tumor Meningiomas Papova-Virus 


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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • A. F. Weiss
    • 1
    • 4
  • K. D. Zang
    • 2
  • G. D. Birkmayer
    • 3
  • F. Miller
    • 3
  1. 1.Max-Planck-Institut für PsychiatrieMünchen 40
  2. 2.Fachrichtung HumangenetikUniversität des SaarlandesHomburg
  3. 3.Institut für ZellbiologieUniversität MünchenMünchenGermany
  4. 4.Institut für Humangenetik der Universität des SaarlandesHomburgFederal Republic of Germany

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