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In vitro biosynthesis, isolation, and activities of nuclear glycoproteins


It has been shown by HPLC, electrophoresis, etc., that, in vitro, the nuclei of neurons of rabbit and cow brains synthesize two glycoproteins (M 25–30 kDa and 10–15 kDa). The influence of some neurotropic compounds on the kinetics of the nuclear protein synthesis has been investigated. New inhibitors of this biosynthesis have been found.

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A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax 627071. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 112–118, January–February, 1994.

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Saitmuratova, O.K., Leont'ev, V.B. & Turakulov, Y.K. In vitro biosynthesis, isolation, and activities of nuclear glycoproteins. Chem Nat Compd 30, 104–108 (1994).

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  • Organic Chemistry
  • Protein Synthesis
  • Nuclear Protein
  • Nuclear Protein Synthesis