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Geschlechtsbestimmung am Zellkern zur Klärung der Pathogenese der Teratome und Hodengeschwülste

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The method of the determination of cell sex by nuclear chromatin studies was used to investigate the nature of 17 teratomas and 10 testicula tumors. The teratomas from women were found to be always of the female sex. A half of those from men were masculine tumors, and the other half were of the female sex. This relationship did not hold for those seminomas which we studied. From our results it seems unlikely that the seminoma is of a teratomatous nature. Teratomas and teratoid tumors of the testis are similar to teratomas of other parts of the body as regards their sex type.

We found in a testicular tumor with both seminoma-like and immature carcinomatour regions cell nuclei of the female type. On the basis of this observation we believe that in embryonal teratomas, besides the carcinomatous and chorionepitheliomatous cells, seminoma-like cells can also arise.

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  1. Albertini, A. v., u.U. V. Schnyder: Bemerkungen zur Frage der embyronalen Hodenteratome. Schweiz. Z. Path. u. Bakter.14, 457 (1951).

  2. Cruickshank, D. B. Sex of mediastinal Teratomata. Lancet1955I 253.

  3. Ewing, J.: Neoplastic diseases. Philadelphia: W. B. Saunders 1928.

  4. Hunter, W. F., andB. Lennox: The sex of Teratomata. Lancet1954II, 633.

  5. Michalowski, I.: Eine experimentelle Erzeugung teratoider Geschwülste der Hoden beim Hahn. Virchows Arch.267, 27 (1928).

  6. Moore, K. L., u.M. L. Barr: Nuclear morphology, according to sex, in human tissues. Acta anat. (Basel)21, 197 (1954).

  7. Oberndorfer, S.: Handbuch der speziellen pathologischen Anatomie und Histologie vonHenke-Lubarsch, Bd. VI, Teil3, S. 427. Berlin: Springer 1931.

  8. Rodermund, O. E.: Über das Geschlechtschromatin in Geschwülsten. Z. Krebsforsch.61, 259 (1956).

  9. Schnyder, U. V.: Beiträge zur Lehre der chrialen Carcinome des Hodens. Schweiz. Z. Path. u. Bakter.14, 298 (1951).

  10. Tavares, A. S.: On the sex of cancer and teratomata cells. Lancet1955I, 948.

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Mancini, A.M. Geschlechtsbestimmung am Zellkern zur Klärung der Pathogenese der Teratome und Hodengeschwülste. Z Krebs-forsch 61, 376–380 (1956). https://doi.org/10.1007/BF00632988

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