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Reactions affecting the γ-lactone ring of α-santonin

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The selective dehydrogenation of the eudesmanolide α-santonin and its alkylation with the introduction of an allyl fragment into its γ-lactone ring are described. It has been established that these reactions are regio- and stereo-selective. The structures of the compounds obtained were determined from their IR, UV, PMR, and mass spectra.

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Additional information

Institute of Organic Synthesis and Coal Chemistry, Kazakhstan Academy of Sciences, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 518–522, September–October, 1992.

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Adekenov, S.M., Gafurov, N.M. Reactions affecting the γ-lactone ring of α-santonin. Chem Nat Compd 28, 452–455 (1992). https://doi.org/10.1007/BF00630648

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  • Sesquiterpene Lactone
  • Diselenide
  • Isopropylamine
  • Exomethylene
  • Diphenyl Diselenide