Chemistry of Natural Compounds

, Volume 29, Issue 3, pp 341–345 | Cite as

Synthesis based on β-phenylethylamines. IV. Synthesis and antiarrhythmic activity of substituted phenylalkylamines and N-benzyltetrahydroisoquinolines

  • V. I. Vinogradova
  • T. I. Golodnyuk
  • N. Tulyaganov
  • M. S. Yunusov
  • N. Yu. Baratov
Article
  • 32 Downloads

Abstract

A number of N-benzyltetrahydroisoquinolines forming analogues of sendaverine have been synthesized. Results on the pharmacological activity of the compounds synthesized are presented.

Keywords

Antiarrhythmic Activity Aconitine Tetrahydroisoquinoline Isoquinoline Alkaloid Sodium Tetrahydroborate 

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References

  1. 1.
    L. N. Yakhontov and S. S. Liberman,Khim.-farm. Zh., No. 11, 1306 (1985); L. N. Yakhontov and S. S. Liberman,Khim.-farm. Zh., No. 3, 269 (1987).Google Scholar
  2. 2.
    H. Landman and H. Lowe,Pharmazie, No. 3, 169 (1986).Google Scholar
  3. 3.
    T. Macao and K. Muzuo,J. Pharm. Soc. Jpn. 85 77 (1965).CrossRefGoogle Scholar
  4. 4.
    M. Shamma,The Isoquinoline Alkaloids Academic Press, New York (1972), p. 495.Google Scholar
  5. 5.
    P. Pant, K. P. Madhusudanan, and D. S. Bhakani,Indian J. Chem. 25B 630 (1986).Google Scholar
  6. 6.
    T. I. Golodnyuk, V. I. Vinogradova, and M. S. Yunusov,Khim. Prir. Soedin., 281 (1990).Google Scholar
  7. 7.
    T. Kametani, K. Fukumoto, S. Shibuya, H. Nemoto, T. Nakano, T. Sugahara, T. Takahashi, and J. Aizawa,J. Chem. Soc., Perkin Trans I. No. 12, 1435 (1972).Google Scholar
  8. 8.
    V. I. Vinogradova and M. S. Yunusov,Khim. Prir. Soedin., 818 (1985).Google Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • V. I. Vinogradova
  • T. I. Golodnyuk
  • N. Tulyaganov
  • M. S. Yunusov
  • N. Yu. Baratov

There are no affiliations available

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