The dimeric sesquiterpene lactone mikagoyanolide (I) has been isolated from the plantTanacetopsis mucronata. The spatial structure of (I) has been determined by the x-ray structural method (R=0.086, 1161 reflections). The dimeric lactone is formed from cyclodecadienes of the germacrolide and melampolide types having chair-chair and boat-chair conformations. The conformational state of the free molecule of (I) has been calculated by the method of molecular mechanics.
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Makhmudov, M.K., Tashkhodzhaev, B. & Abduazimov, B.K. Spatial structure of the dimeric sesquiterpene germacrane lactone mikagoyanolide. Chem Nat Compd 29, 174–178 (1993). https://doi.org/10.1007/BF00630109
- Organic Chemistry
- Molecular Mechanic
- Spatial Structure
- Conformational State