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Spatial structure of the dimeric sesquiterpene germacrane lactone mikagoyanolide

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Abstract

The dimeric sesquiterpene lactone mikagoyanolide (I) has been isolated from the plantTanacetopsis mucronata. The spatial structure of (I) has been determined by the x-ray structural method (R=0.086, 1161 reflections). The dimeric lactone is formed from cyclodecadienes of the germacrolide and melampolide types having chair-chair and boat-chair conformations. The conformational state of the free molecule of (I) has been calculated by the method of molecular mechanics.

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Additional information

Institute of Chemistry of Plant Substances, Uzbekistan Republic of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 213–217, March–April, 1993.

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Makhmudov, M.K., Tashkhodzhaev, B. & Abduazimov, B.K. Spatial structure of the dimeric sesquiterpene germacrane lactone mikagoyanolide. Chem Nat Compd 29, 174–178 (1993). https://doi.org/10.1007/BF00630109

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Keywords

  • Organic Chemistry
  • Molecular Mechanic
  • Spatial Structure
  • Lactone
  • Conformational State