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Cembrenolides of a soft coral Lobophytum sp. (coelenterata, octocorallia, alcyonacea)

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The known cembrenolide sarcophin and its new acetoxy derivative — 13-acetoxy-7,8-epoxycembra-1(15),3,11-trien-2,16-olide — have been isolated from the soft coralLobophytum sp.. The compounds isolated are inhibitors of the activity of Na+K+-ATPase and are membranotropic agents. The structures of the compounds have been shown on the basis of the results of NMR spectroscopy.

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Additional information

Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Branch, Academy of Sciences of the USSR, Vladivostok. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 762–765, November–December, 1990.

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Suleimenova, A.M., Kuznetsova, T.A., Denisenko, V.A. et al. Cembrenolides of a soft coral Lobophytum sp. (coelenterata, octocorallia, alcyonacea). Chem Nat Compd 26, 647–650 (1990). https://doi.org/10.1007/BF00630073

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  • Soft Coral
  • Acetoxy
  • Butenolide
  • Acetoxy Group
  • Specific Optical Rotation