Effect of capsule colour and order of administration of hypnotic treatments
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Ninety-six hospitalized insomniac patients were asked to compare by a daily questionnaire the effect on sleep of the colour of the capsules and the order of administration of two treatments — heptabarbital and placebo. A balanced incomplete-block design was used; sleep onset time and sleep duration time were the main criteria of assessment. There was a significant interaction of colour and order of administration with sex. The placebo response was positive in 36% of instances.
Key wordsHeptabarbital drug colour order of administration sex-linked response placebo response rate
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