It has been established that in the transformation of natural pyrimidine bases and 5-halouracils by strains of the genus Mycobacterium the following are formed as intermediates: from uracil, cytosine, and 5-iodouracil, barbituric acid; from thymine, 5-methylbarbituric aicd; and from 5-fluoro-, 5-chloro-, and 5-bromouracils, the corresponding 5-halobarbituric acids.
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Vitol, M.Y., Shaposhnikov, V.N., Duntse, M.E. et al. The chemical structure of the products of the transformation of natural pyrimidine bases and 5-halouracils by mycobacteria. Chemistry of Heterocyclic Compounds 4, 257–259 (1970). https://doi.org/10.1007/BF00601145
- Organic Chemistry