To evaluate the effectiveness of CT and MRI at 0.5 T in the diagnosis and staging of retinoblastoma, we studied 11 patients in whom retinoblastoma was clinically suspected. Nine of the eleven had surgically proven retinoblastoma; in the other two a diagnosis of Coat's disease was made. MRI was not as specific as CT for diagnosing retinoblastoma, due to its lack of sensitivity in detecting calcification; it did, however, have superior contrast resolution. On MRI, Coats' discase was reliably diagnosed and easily differentiated from retinoblastoma. Moreover, the greater ability of MRI to differentiate subretinal fluid from tumour also confers high accuracy in measuring tumour size. CT is still the study of choice in the diagnosis of retinoblastoma, but when MRI is available, it should be performed for better differentiation from lesions such as Coats' disease.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Mafee MF (1990) Magnetic resonance imaging: ocular pathology. In: Newton TH, Bilaniuk LT. Radiology of the eye and orbit (Modern neuroradiology, volume 4). Raven Press, New York, pp 311–314, 321–322
Donaldson SS, Smith LM (1989) Retinoblastoma: biology, presentation and current management. Oncology 3:45–52
Abramson DH (1982) Retinoblastoma: diagnosis and management. CA 32: 130–140
Mafee MF, Goldberg MF, Cohen SB, Gotsis ED, Safran M, Chekuri L, Raofi B (1989) Magnetic resonance imaging versus computed tomography of leukocoric eyes and use of in vitro proton magnetic resonance spec troscopy of retinoblastoma. Ophthalmology 96: 965–976
Wilms G, Marchal G, Van Fraeyenhoven L, Demaerel P, Van Hecke P, Baert AL, Dralands G (1991) Shortcomings and pitfalls of ocular MRI. Neuroradiology 33: 320–325
Nucci P, Modorati G, Pierro L, Alfarano R, Brancato R (1989) Comparative evaluation of echography and CAT in diagnosing retinoblastoma. Minerva Pediatr 41: 129–131
Gupta KL, Righi AM, Mihara F, Robinson AE, Haik BG (1991) MRI, ultrasound and surgical correlation of orbital tumors. Neuroradiology 33 [Suppl]: 71
Mafee MF, Goldberg MG, Greenwold JM, et al (1987) Retinoblastoma and simulating lesions: role of CT and MR imaging. Radiol Clin North Am 25: 667–682
Wilms G, Dralands G, Van Fraeyenhoven L, Decrop E, Demaerel P, Van Eyck L, Marchal G, Van Hecke P, Baert AL (1989) Magnetic resonance imaging in lesions of the eye globe. J Belge Radiol 72: 165–172
Peyster RG, Augsberger JJ, Shields JA, Hershey BL, Eagle R, Haskin ME (1988) Intraocular tumors: evaluation with MR imaging. Radiology 168: 773–779
Peyster RG, Augsburger JJ, Shields JA, Herskey BL, Eale R Jr, Haskin ME (1988) Intraocular tumors: evaluation with MR imaging. Radiology 168: 773–779
Weber AL, Mafee MF (1992) Evaluation of the globe using computed tomography and magnetic resonance imaging. Israel J Med Sci 23: 145–152
Holland BA, Kucharczyk W, Brant-Zawadski M, Norman D, Haas DK, Harper PS (1985) MR imaging of calcified intracranial lesions. Radiology 157: 353–356
Oot RF, New PFJ, Pile-Spellman J, Rosen BR, Shoukimas GM, Davis KR (1986) Detection of intracranial calcifications by MR. AJNR 7: 801–809
Edwards JH, Hyman RA, Vacirca SJ, et al (1985) 0.6 T magnetic resonance imaging of the orbit. AJR 144: 1015–1020
Sobel DF, Kelly W, Kjos BO, Char D, Brant-Zawadski M, Norman D (1985) MR imaging of orbital and ocular disease. AJNR 6: 259–264
Haik BG, Saint Louis L, Smith ME et al. (1985) Magnetic resonance imaging in the evaluation of leukocoria. Ophthalmology 92: 1143–1152
Sullivan JA, Harms SE (1987) Characterization of orbital lesions by surface coil MR imaging. Radiographics 7: 9–28
Sullivan JA, Harms SE (1986) Surface coil MR imaging of orbital neoplasm. AJNR 7: 29–34
Scott WA, Bilaniuk LT, Zimmerman RA, Hackney DB, Goldberg HI, Grossman RI (1987) Orbit: initial experience with surface coil spin echo MR imaging at 1.5 T. Radiology 164: 501–509
Okabe H, Kiyosowa M, Mizuno K, Yamada S, Yamada K (1986) Nuclear magnetic resonance imaging of subretinal fluid. Am J Ophthalmol 102: 640–646
Smith EV, Gragoudas ES, Kolodny NH, Amico DJ (1990) Magnetic resonance imaging: an emerging technique for the diagnosis of ocular disorders. Int Ophth 14: 119–124
About this article
Cite this article
Beets-Tan, R.G.H., Hendriks, M.J., Ramos, L.M.P. et al. Retinoblastoma: CT and MRI. Neuroradiology 36, 59–62 (1994). https://doi.org/10.1007/BF00599199
- Coats' disease