Solid-phase triester synthesis of modified triuridylates using an effective condensing agent
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Abstract
Triuridylates containing 2′-deoxyuridine, 5-bromouridine, and 6-azauridine in various positions of the sequence have been synthesized by the use of an O-nucleophilic nucleotide condensation catalyst — 4-ethoxypyridine N-oxide — under the conditions of the solid-phase triester method.
Keywords
Nucleotide Organic Chemistry Deoxyuridine Condensation Catalyst Nucleotide Condensation
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© Plenum Publishing Corporation 1988