Abstract
The known natural diglycoside convalloside — strophanthidin 3β-O-[4-O-β-d-glucopyranosyl-α-L-rhamnopyranoside] — has been synthesized. The synthesis was carried out by the Koenigs-Knorr method via the preparation as intermediates of convallatoxin and its 2,3-isopropylidene derivative. Selectivity of glycosylation was achieved by the preliminary protection of the two OH groups in the cardenolide L-rhamnoside (convallatoxin).
Keywords
Organic Chemistry Cardenolide Strophanthidin Convallatoxin Convalloside
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© Plenum Publishing Corporation 1988