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European Radiology

, Volume 2, Issue 3, pp 244–246 | Cite as

White matter lesions in psychiatric patients: a retrospective MRI study

  • T. Becker
  • E. Teichmann
  • E. Hofmann
  • A. Schmidtke
  • M. Warmuth-Metz
  • M. Nadjmi
Neuroradiology

Abstract

T2-weighted MRI scans of psychiatric patients with at least one white matter lesion (WML) were compared to 83 non-psychiatric controls with respect to WML number and distribution. MANOVA results in significant effects for sex, age and patient group with respect to WML number. In the psychiatric patients, infratentorial WML prevailed in organic psychoses. WML number was positively correlated with age with the exception of rith temporal lobe WML. Based on WML spatial distribution, four patient clusters were found. Clusters with widely distributed WML comprised older patients with late onset of illness; right frontal and temporal WML were associated with mania, euphoria and unstable mood.

Key words

MRI Psychiatry white matter 

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • T. Becker
    • 1
    • 2
  • E. Teichmann
    • 1
  • E. Hofmann
    • 1
  • A. Schmidtke
    • 2
  • M. Warmuth-Metz
    • 1
  • M. Nadjmi
    • 1
  1. 1.Department of NeuroradiologyUniversity of WürzburgWürzburgGermany
  2. 2.Department of PsychiatryUniversity of WürzburgWürzburgGermany

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