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Fresenius' Zeitschrift für analytische Chemie

, Volume 317, Issue 2, pp 101–114 | Cite as

Polycyclic aromatic compounds of environmental and occupational importance — Their occurrence, toxicity and the development of high purity certified reference materials. Part I

  • J. Jacob
  • W. Karcher
  • P. J. Wagstaffe
Review

Summary

The paper describes the preparation and certification for calibration and reference purposes of 41 compounds of the polycyclic aromatic compounds (PAC) class of environmental and occupational pollutants. The compounds were selected on the basis of their occurrence and biological activities. A summary review of principal sources of occurrence and available data on mutagenic and carcinogenic activities is presented. Also, the analytical procedures for the purity determinations are discussed and evaluated, and some physicochemical data (melting points, UV-maxima and corresponding molar absorption coefficients) are given for the PAC-compounds considered.

Keywords

Toxicity Inorganic Chemistry Absorption Coefficient Melting Point Biological Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Polycyclische aromatische Verbindungen im Zusammenhang mit Umwelt und Arbeit — ihr Vorkommen, ihre Toxizität und die Entwicklung von hochreinen zertifizierten Referenzmaterialien. Teil I

Zusammenfassung

Die Herstellung und Zertifizierung von 41 polycyclischen aromatischen Verbindungen, die von Bedeutung als Verunreinigung in der Umwelt und am Arbeitsplatz sind, wird beschrieben. Die Verbindungen wurden nach ihrem Vorkommen und ihrer biologischen Aktivität ausgewählt. Ein zusammenfassender Überblick wird gegeben über die Ursachen ihres Auftretens sowie über ihre cancerogenen und mutagenen Eigenschaften. Die analytischen Methoden zur Reinheitsbestimmung werden diskutiert und ausgewertet sowie einige physikalisch-chemische Daten (Schmelzpunkte, UV-maxima, molare Extinktionskoeffizienten) angegeben.

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • J. Jacob
    • 1
  • W. Karcher
    • 2
  • P. J. Wagstaffe
    • 3
  1. 1.Biochemisches Institut für UmweltcarcinogeneAhrensburgFederal Republic of Germany
  2. 2.Commission of the EC, JRC, Petten EstablishmentZG PettenThe Netherlands
  3. 3.Community Bureau of ReferenceCommission of the ECBrusselsBelgium

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