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Effects on rats of CSF from sleep-deprived rabbits

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Rabbits were sleep-deprived for 72 hours in revolving drum sleep deprivation cages. Cerebrospinal fluid samples obtained from these sleep-deprived and from control rabbits were infused intraventricularly into rats to assay for the presence of a sleep-promoting material in the sleep-deprived rabbit CSF. Effects on ECoG patterns, ambulatory activity and behavior of the assay rats failed to show sleep-promoting properties for the CSF from sleep-deprived rabbits.

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Ringle, D.A., Herndon, B.L. Effects on rats of CSF from sleep-deprived rabbits. Pflugers Arch. 306, 320–328 (1969). https://doi.org/10.1007/BF00589157

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  • Sleep
  • Sleep Deprivation
  • Cerebrospinal Fluid
  • ECoG Recording
  • Ambulatory Activity


  • Schlaf
  • Schlafberaubung
  • Cerebrospinalflüssigkeit
  • Elektrocorticogramm
  • Ambulante Bewegungen