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  • Transport Processes, Metabolism and Endocrinology; Kidney, Gastrointestinal Tract, and Exocrine Glands
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NaCl transport across hen colon

Dependence on electro-chemical driving force

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  • 10 Citations

Abstract

  1. 1.

    Sheets of isolated mucosa from the colon of chickens on either a high or a low NaCl diet were mounted in Ussing chambers. They were bathed in Krebs-phosphate medium and exposed to sodium concentrations ranging from 3.0 to 140 mmol/l (choline-chloride replacement).

  2. 2.

    In the short-circuited state the net fluxes of sodium in the mucosa (m)-serosa (s) direction, followed saturation kinetics withK m =25 mmol/l in the low-NaCl chickens and 124 mmol/l in the high-NaCl chickens.

  3. 3.

    The unidirectional fluxes of sodium in the s-m direction were linearly related to the electro-chemical driving force. The apparent permeabilities were 8.6±0.3×10−6cm/s in the low-NaCl and 11.6±0.3×10−6cm/s in the high-NaCl birds.

  4. 4.

    The chloride fluxes were in the short-circuited state of equal magnitude in the m-s and the s-m direction, and in the two dietary states. Changes in the electrical driving force resulted in changes in chloride fluxes compatible with passive flow.

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References

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  5. Lyngdorf-Henriksen P, Munck BG, Skadhauge E (1978) Sodium chloride transport across the lower intestine of the chicken Dependence on sodium chloride concentration and effect of inhibitors. Pflügers Arch 378:161–165

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Correspondence to E. Skadhauge.

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Holtug, K., Skadhauge, E. NaCl transport across hen colon. Pflugers Arch. 394, 222–225 (1982). https://doi.org/10.1007/BF00589095

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Key words

  • Intestine
  • NaCl transport
  • Bird osmoregulation