Olivary degeneration after cerebellar or brain stem haemorrhage: MRI
Magnetic resonance (MR) images of seven patients with olivary degeneration caused by cerebellar or brain stem haemorrhages were reviewed. In four patients with cerebellar haemorrhage, old haematomas were identified as being located in the dentate nucleus; the contralateral inferior olivary nuclei were hyperintense on proton-density- and T2-weighted images. In two patients with pontine haemorrhages, the old haematomas were in the tegmentum and the ipsilateral inferior olivary nuclei, which were hyperintense. In one case of midbrain haemorrhage, the inferior olivary nuclei were hyperintense bilaterally. The briefest interval from the ictus to MRI was 2 months. Hypertrophic olivary nuclei were observed only at least 4 months after the ictus. Olivary degeneration after cerebellar or brain stem haemorrhage should not be confused with ischaemic, neoplastic, or other primary pathological conditions of the medulla.
Key wordsOlivary degeneration Cerebellar haemorrhage Brain stem haemorrhage Magnetic resonance imaging
Unable to display preview. Download preview PDF.
- 1.Guillain G, Mollaret P (1931) Deux cas de myoclonies synchronés et rythmées vélo-pharyngo-laryngo-oculo-diaphragmatiques. Le probleme anatomique et physio-pathologique de ce syndrome. Rev Neurol 2: 545–566Google Scholar
- 2.Gautier JC, Blackwood W (1961) Enlargement of the inferior olivary nucleus in association with lesions of the central tegmental tract or dentate nucleus. Brain 84: 341–361Google Scholar
- 3.Jellinger K (1973) Hypertrophy of the inferior olives. Report on 29 cases. Z Neurol 205: 153–174Google Scholar
- 4.Sperling MR, Herrmann C, Jr (1985) Syndrome of palatal myoclonus and progressive ataxia: two cases with magnetic resonance imaging. Neurology 35: 1212–1214Google Scholar
- 5.Yokota T, Hirashima F, Furukawa T, Tsukagoshi H, Yoshikawa H (1989) MRI findings of inferior olives in palatal myoclonus. J Neurol 236: 115–116Google Scholar
- 6.Hirono N, Kameyama M, Kobayashi Y, Udaka F, Mezaki T, Abe K, Nishitani N (1990) MR demonstration of a unilateral olivary hypertrophy caused by pontine tegmental hematoma. Neuroradiology 32: 340–342Google Scholar
- 7.Zarranz JJ, Fontan A, Forcadas I (1990) MR imaging of presumed olivary hypertrophy in palatal myoclonus. AJNR 11: 1164Google Scholar
- 8.Dubinsky RM, Hallett M, Di Chiro G, Fullham M, Schwankhaus J (1991) Increased glucose metabolism in the medulla of patients with palatal myoclonus. Neurology 41: 557–562Google Scholar
- 9.Revel MP, Mann M, Brugières P, Poirier J, Gaston A (1991) MR appearance of hypertrophic olivary degeneration after contralateral cerebellar hemorrhage. AJNR 12: 71–72Google Scholar
- 10.Bontozoglou NP, Chakeres DW, Martin GF, Brogan MA, McGhee RB (1991) Cerebellorubral degeneration after resection of cerebellar dentate nucleus neoplasms: evaluation with MR imaging. Radiology 180: 223–228Google Scholar
- 11.Pierot L, Cervera-Pierot P, Delattre J-Y, Duyckaerts C, Chiras J, Brunet P (1992) Case report. Palatal myoclonus and inferior olivary lesions. MRI-pathologic correlation. J Comput Assist Tomogr 16: 160–163Google Scholar
- 12.Goto N, Kaneko M (1981) Olivary enlargement: chronological and morphometric analyses. Acta Neuropathol (Berl) 54: 275–282Google Scholar