Atypical demyelinating lesions in patients with multiple sclerosis
Diagnostic Neuroradiology
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Abstract
We describe an atypical MRI appearance of multiple sclerosis (MS). Lesions characterized on T2-weighted images by a well-defined rim of increased signal intensity and a concentric region of higher signal intensity were seen in 6 of 132 patients with MS. On T1-weighted images these lesions were evident as regions of low signal intensity, often with a rim of contrast enhancement or increased signal intensity. These appearances tended to be shown by new, evolving lesions.
Key words
Demyelination Multiple sclerosis Magnetic resonance imagingPreview
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References
- 1.Robertson WD, Li DKB, Mayo JR, et al (1987) Assessment of multiple sclerosis lesions by magnetic resonance imaging. J Can Assoc Radiol 38:177–182Google Scholar
- 2.Jacobs L, Kinkel WR, Polachini I et al (1987) Correlations of nuclear magnetic resonance imaging, computerized tomography, and clinical profiles in multiple sclerosis (abstract). Radiology 162: 888Google Scholar
- 3.Stevens JC, Farlow MR, Edwards MK, et al (1987) Magnetic resonance imaging: clinical correlation in 64 patients with multiple sclerosis (abstract). Radiology 163: 592Google Scholar
- 4.Kappos L, Stadt D, Ratzka M, et al (1988) Magnetic resonance imaging in the evaluation of treatment in multiple sclerosis. Neuroradiology 30:299–302Google Scholar
- 5.Appel B, Moens E, Rinck P et al (1988) MRI approach of multiple sclerosis: 449 cases examined at 0.15 tesla. Neuroradiology 15:108–136Google Scholar
- 6.Uhlenbrock D, Seidel D, Gehlen W, et al (1988) MR imaging in multiple sclerosis: comparison with clinical, CSF, and visual evoked potential findings. AJNR 9:59–67Google Scholar
- 7.Poser CM, Kleefield J, O'Reilly GV, et al (1987) Neuroimaging and the lesion of multiple sclerosis. AJNR 8:549–552Google Scholar
- 8.Horowitz AL, Kaplan RD, Grewe G, et al (1989) Ovoid lesion: a new MR observation in patients with multiple sclerosis. AJNR 10:303–305Google Scholar
- 9.Grossman RI, Braffman BH, Brorson JR, Goldberg HI, Silberberg DH, González-Scarano F (1988) Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. Radiology 169:117–122Google Scholar
- 10.Paty DW, Oger SSF, Kastrukey LF, et al (1988) MRI in the diagnosis of MS. A prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding and CT. Neurology 38:180–184Google Scholar
- 11.Miller DH, Rudge P, Johnson G, et al (1988) Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. Brain 111:927–939Google Scholar
- 12.Kermode AG, Tofts PS, McManus DG, et al (1988) Early lesion of multiple sclerosis. Lancet II: 1203–1204Google Scholar
- 13.Dousset J, Grossman RI, Ramer KN, Schnall MP, Young LH, González-Scarano F, Lavi E, Cohen JA (1992) Experimental allergic encephalomyelitis: lesion characterization with magnetization transfer imaging. Radiology 182:483–491Google Scholar
- 14.Nesbit GM, Forbes GS, Scheithauer BW (1991) Multiple sclerosis: histopathologic and MR and/or CT correlation in 37 cases at biopsy and 3 cases at autopsy. Radiology 180:467–474Google Scholar
- 15.Powell T (1992) MR imaging in acute multiple sclerosis: ring-like appearance in plaques suggesting the presence of paramagnetic free radicals. AJNR 13: 1544–1546Google Scholar
- 16.Paty DW, Asbury AK, Herndon PM, et al (1986) Use of magnetic resonance imaging in the diagnosis of multiple sclerosis: policy statement (abstract). Neurology 36:1575Google Scholar
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