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Magnetic resonance imaging of the brain in congenital rubella virus and cytomegalovirus infections

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Summary

Two children with congenital rubella virus and six with cytomegalovirus (CMV) infections, were examined by magnetic resonance (MR) and CT. Cranial MR imaging (MRI) with T2-weighted spin-echo (SE) and inversion recovery (IR) sequences demonstrated the following: periventricular hyperintensity (4), subcortical hyperintensity (5), delayed myelination (4), oligo/pachygyria (2), cerebellar hypoplasia (2). This study showed that the more-disabled children had more marked abnormal MRI findings. MRI was more effective in the detection of parenchymal lesion than was CT, although intraventricular calcification was better visualized with CT.

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Sugita, K., Ando, M., Makino, M. et al. Magnetic resonance imaging of the brain in congenital rubella virus and cytomegalovirus infections. Neuroradiology 33, 239–242 (1991). https://doi.org/10.1007/BF00588225

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Key words

  • Congenital infection
  • Cytomegalovirus
  • Rubella
  • Central nervous system (CNS)
  • Magnetic resonance imaging (MRI)