Diabetologia

, Volume 34, Supplement 1, pp S16–S17

Outcome of renal grafts after simultaneous kidney/ pancreas transplantation

  • G. Hillebrand
  • W. -D. Illner
  • D. Abendroth
  • H. Schneeberger
  • I. Petry
  • S. Schleibner
  • R. Landgraf
  • W. Land
Outcome of Pancreatic Transplantation

Summary

Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique. Another group of 25 Type 1 diabetic patients received pancreas/kidney transplants by the duct occlusion technique. We observed a higher incidence of rejection episodes in the patients of the bladder drainage group than those in the duct occlusion group, 14 of 19 patients (74%) vs 7 of 25 (28%) respectively. Anti CD3 antibodies (Orthoclone, OKT3) as a part of induction treatment was used more often in the bladder drainage group (58%) than in the control group (20%).

Key words

Pancreas/kidney transplantation Diabetes mellitus Bladder drainage technique Renal rejection episode 

References

  1. Castro LA, Landgraf R, Hillebrand G, Land W (1986) Causes of renal graft dysfunction in diabetics after simultaneous pancreas and kidney transplantation. Transpl.Proc. 18:1733–1734Google Scholar
  2. Hillebrand O, Castro LA, Landgraf R, Schleibner S, Illner WD, Abendroth D, Land W (1987) Combined/kidney pancreas transplantation — poor long-term outcome of renal grafts. Transpl.Proc. 19:3909–3910Google Scholar
  3. Illner WD, Abendroth D, Landgraf R, Land W (1991) Long-term results in pancreatic transplantation with special emphasis on the use of prolamin. Diabetologia 34 [Suppl 2]Google Scholar
  4. Knechtle SJ, Pirsch JD, Groshek M, et al. (1991) OKT3 vs ALG induction therapy in combined pancreas-kidney transplantation. Transpl.Proc. 23:1581–1582Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • G. Hillebrand
    • 1
  • W. -D. Illner
    • 2
  • D. Abendroth
    • 2
  • H. Schneeberger
    • 2
  • I. Petry
    • 2
  • S. Schleibner
    • 2
  • R. Landgraf
    • 3
  • W. Land
    • 2
  1. 1.Nephrology Department, Medical Clinic I, Klinikum GrosshadernUniversity of MunichMunichGermany
  2. 2.Division of Transplant Surgery, Klinikum GrosshadernUniversity of MunichMunichGermany
  3. 3.Medical Clinic “Innenstadt”University of MunichMunichGermany

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