Teratocarcinogenesis as related to the age of embryos grafted under the kidney capsule

  • Ivan Damjanov
  • Davor Solter
  • Nikola Škreb
Short Communications


Mouse egg-cylinders of C3H/H strain with two and three germ layers were transplanted under the kidney capsule. They developed into well differentiated teratomas and teratocarcinomas. Older embryos developed invariably into teratomas composed of adult tissues only. We consider the period of germ layer inversion as a critical stage when embryonic cells loose their potentiality for uncontrolled growth.


Developmental Biology Teratoma Adult Tissue Embryonic Cell Germ Layer 
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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • Ivan Damjanov
    • 1
    • 2
  • Davor Solter
    • 1
  • Nikola Škreb
    • 1
  1. 1.Institute of BiologyUniversity of ZagrebCroatia
  2. 2.Department of PathologyMedical FacultyZagrebYugoslavia

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