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  • Heart, Circulation, Respiration and Blood; Environmental and Exercise Physiology
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The CO single breath transfer factor of the lung

Generally acceptable normal values


The CO single breath method for determining the transfer factor of the lung,T, and its component factors,Dm andVc, never gained wide application. The lack of generally accepted normal values has contributed to this. In this paper, based on the results of measurements in 28 normal subjects, it is shown that generally acceptable normal values can be obtained by: 1. determiningT at lung volumes above 80% TLC, and 2. expressingT, Dm andVc per unit of alveolar gas volume during breath-holding:T v ,Dm v andVc v .

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Correspondence to F. Werner.

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Werner, F., Beneken Kolmer, H. The CO single breath transfer factor of the lung. Pflugers Arch. 393, 269–274 (1982).

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Key words

  • Lung function
  • Transfer factor
  • Single breath method
  • Normal values