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Pflügers Archiv - European Journal of Physiology

, Volume 413, Issue 3, pp 316–318 | Cite as

The slow inward calcium current is responsible for a part of the contraction of patch-clamped rat myoballs

  • Michèle Rivet
  • Christian Cognard
  • Guy Raymond
Excitable Tissues Cand Central Nervous Physiology Short Communication

Abstract

The slow inward calcium current and the contractile response were simultaneously recorded in voltage clamped (whole cell patch clamp recording) rat myoballs in primary culture.

The shape of the contraction(T)/potential(V) relationship and the application of the inorganic calcium channel blocker cadmium (1.5 mM), which suppresses a part of the contractile activity, demonstrate the existence of two components of contraction. One of them is related to the slow calcium current.

Key words

Rat skeletal muscle cell culture patch clamp calcium currents contraction 

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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Michèle Rivet
    • 1
  • Christian Cognard
    • 1
  • Guy Raymond
    • 1
  1. 1.Laboratory of General Physiology, CNRS U.A. 290University of PoitiersPoitiers CedexFrance

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