Direct measurements of oxygen tension at the surface of arterioles, capillaries and venules of the cerebral cortex
- 58 Downloads
Direct pO2 measurements were made at the surface of arterioles, capillaries, and venules of rabbit brain cortex. The results indicate that a considerable amount of oxygen diffuses through the arteriolar and precapillary wall. Therefore, the arterial blood that reaches the capillaries already has low pO2 (43±3 mm Hg and about 75%–70% of the blood oxygen capacity).
Key wordsArteriolar and precapillary O2 diffusion capillary pO2 brain cortex microvessels
Unable to display preview. Download preview PDF.
- Bartels H., Harms H. Sauerstoffdissoziationskurven des Blutes von Säugetieren. Pflügers Arch.,268, 334–365 (1959)Google Scholar
- Davies P.W., Bronk D.W. Oxygen tension in mammalian brain. Fed.Proc.16, 3, 669–678 (1957)Google Scholar
- Duling B.R., Berne R.M. Longitudinal gradients in periarteriolar oxygen tension. Circ.Res.,27, 5, 669–678 (1970)Google Scholar
- Duling B.R., Berne R.M. and Wahl M. Measurements of the perivascular pO2 in the vicinity of pial vessels of the cat. Pflügers Arch.,383, 29–34 (1979)Google Scholar
- Grunewald W.A., Lübbers D.W. Kryomicrophotometry as a method for analysing the intracapillary HbO2 saturation of organs under different O2 supply conditions. Adv.Exp.Med.Biol.75, 55–64 (1976)Google Scholar
- McCusky R.S., Meineke H.D. and Townsend S.F. Studies of the hemopoetic microenvironment 1. Changes in the microvasculature system and stroma during erythropoietic regeneration and suppression in the spleens of CFJ mice. Blood,39, 697–712 (1965)Google Scholar
- Metzger H. Qualities of the microcirculatory transport system of the rat brain cortex analysed by means of oxygen microelectrode measurements and theoretical calculations of the pO2 field. In: 2nd World Congress for microcirculation. Microvasc.Res.,17, 3, S1–S183 (1979)Google Scholar
- Samoilov M.O. A method of morphological identification of individual neurons in the brain in vivo and after fixation. Microscopic Acta,79, 4, 348–352 (1977)Google Scholar
- Samoilov M.O., Semionov D.G. Intravital microscopic study of the cerebral cortex. In: Intravital microscopy of the neurons. Leningrad, Nauka, 1978, p. 58–72 (in Russian)Google Scholar
- Stosseck K. Hydrogen exchange through the pial vessel wall and its meaning for the determination of the local cerebral blood flow. Pflügers Arch.320, 111–119 (1970)Google Scholar
- Whalen W.J., Riley J. and Nair P. A microelectrode for measuring intracellular pO2. J.Appl.Physiol.23, 5, 798–801 (1967)Google Scholar