Pflügers Archiv

, Volume 362, Issue 3, pp 219–222

Oxygen uptake of rats at different work intensities

  • R. E. Shepherd
  • P. D. Gollnick


An adaptation of a standard activity wheel has been used to determine oxygen uptake of rats prior to and during exercise at 7 different speeds (16–67 m/min). Pre-exercise oxygen uptake was 2.42±0.10 (S.E.) ml (100 g×min)−1 Oxygen uptake increased linearly with work intensity (running speed). At 16 m/min oxygen uptake was 6.44±0.16 ml (100 g×min)−1 and it increased to a maximal value of 9.51±0.14 ml (100 g×min)−1 at a running speed of 53.6 m/min. Increasing running speed to 67 m/min did not produce any further increas in oxygen uptake. Some comparisons of exercise intensity between rats of various studies and rats and man can be made from these data.

Key words

Oxygen uptake Work intensity Aerobic power of rats 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Anderson, K. L.: The cardiovascular system in excrcise. In: Exercise physiology (H. B. Falls, ed.), pp. 79–128. New York: Academic Press 1968Google Scholar
  2. 2.
    Armstrong, R. B., Saubert, C. W., IV, Sembrowich, W. L., Shepherd, R. E., Gollnick, P. D.: Glycogen depletion in rat skeletal muscle fibers at different intensities and durations of exercise. Pflügers Arch.352, 243–256 (1974)Google Scholar
  3. 3.
    Baker, M. A., Horvath, S. M.: Influence of water temperature on oxygen uptake by swimming rats. J. appl. Physiol.19, 1215–1218 (1964)Google Scholar
  4. 4.
    Gollnick, P. D., Armstrong, R. B., Saltin, B., Saubert, C. W., IV, Sembrowich, W. L., Shepherd, R. E.: Effect of training on enzyme activity and fiber composition of human skeletal muscle. J. appl. Physiol.34, 107–111 (1973)Google Scholar
  5. 5.
    Gollnick, P. D., Ianuzzo, C. D.: Hormonal deficiences and the metabolic adaptations of rats to training. Amer. J. Physiol.223, 278–282 (1972)Google Scholar
  6. 6.
    Gollnick, P. D., Inauzzo, C. D.: Colonic temperature response of rats during exercise. J. appl. Physiol.24, 747–750 (1968)Google Scholar
  7. 7.
    Hearn, G. R., Wainio, W. W.: Succinic dehydrogenase activity of the heart and skeletal muscle of exercised rats. Amer. J. Physiol.185, 349–350 (1956)Google Scholar
  8. 8.
    Holloszy, J. O.: Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J. biol. Chem.242, 2278–2282 (1967)Google Scholar
  9. 9.
    Krantzing, C. C., Mark, S.: Oxygen consumption in the albino rat. Canad. J. Physiol. Pharmacol.45, 363–365 (1957)Google Scholar
  10. 10.
    McArdle, W. D.: Metabolic stress of endurance swimming in the laboratory rat. J. appl. Physiol.22, 50–54 (1967)Google Scholar
  11. 11.
    Moses, L. E.: Determination of oxygen consumption in the albino rat. Proc. Soc. exp. Biol. (N. Y.)64, 54–57 (1947)Google Scholar
  12. 12.
    Pasquis, P., Dejours, P.: Consommation maximale d'oxygen chez le rat blanc et le cobaye. J. Physiol. (Paris)57, 670 (1965)Google Scholar
  13. 13.
    Popovic, V., Kent, K., Mojovic, N., Mojovic, B., Hart, J. S.: Effect of exercise and cold on cardiac output in warm- and cold-acclimated rats. Fed. Proc.28, 1138–1141 (1969)Google Scholar
  14. 14.
    Ring, G. C.: Adrenalin and the metabolism of exercise. Amer. J. Physiol.97, 375–385 (1931).Google Scholar
  15. 15.
    Taylor, C. R., Schmidt-Nielsen, K., Raab, J. L.: Scaling of energetic cost of running to body size in mammals. Amer. J. Physiol.219, 1104–1107 (1970)Google Scholar
  16. 16.
    Taylor, C. R., Caldwell, S. L., Rowntree, V. J.: Running up and down hills: Some consequences of size. Science178, 1096–1097 (1972)Google Scholar
  17. 17.
    Tipton, C. M., Terjung, R. L., Barnard, R. J.: Response of thyroidectomized rats to training. Amer. J. Physiol.215, 1137–1142 (1968)Google Scholar

Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • R. E. Shepherd
    • 1
  • P. D. Gollnick
    • 1
  1. 1.Department of Physical Education for MenWashington State UniversityPullmanUSA

Personalised recommendations