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Central thermal adaptation of lower brain stem units in the guinea-pig

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Cold adaptive changes were found in single units responding to thermal skin stimulation. All units were located in the subcoeruleus region of the lower brain stem. In cold-adapted guinea-pigs (five weeks in ambient temperature of 4°C), the maximum activity of cold-responsive neurones was reduced markedly in comparison with that of cold-responsive neurones in animals adapted to room temperature (ca. 21°C). This decrease may be a neuronal correlate to long-term downward shifts of shivering threshold temperature known to occur within adaptation periods of several weeks in man, as well as in animals.

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  1. Brück, K. (1981). Basic mechanisms in longtime thermal adaptation. In: Contributions to Thermal Physiology, ed. Szelényi, Z. & Székely, M., pp. 263–273. Budapest: Akadémiai Kiadó & Pergamon Press.

  2. Brück, K. & Hinckel, P. (1980). Thermoregulatory noradrenergic and serotonergic pathways to hypothalamic units. J. Physiol.304, 193–202.

  3. Brück, K. & Wünnenberg, W. (1967). Eine kälteadaptative Modifikation: Senkung der Schwellentemperaturen für Kältezittern. Pflügers Arch.293, 226–235.

  4. Dickenson, A. H. (1977). Specific responses of rat raphé neurones to skin temperature. J. Physiol.273, 277–293.

  5. Hensel, H. & Banet, M. (1978). Thermoreceptor activity, insulative and metabolic changes in cold and warm adapted cats. In: New Trends in Thermal Physiology, ed. Houdas, Y. & Guieu, J. D., pp. 53–55. Paris: Masson.

  6. Hinckel, P., Brück, K. & Schröder-Rosenstock, K. (1981). Thermal adaptation of subcoeruleus single units. Pflügers Arch. Suppl.389, R 36.

  7. Hinckel, P. & Schröder-Rosenstock, K. (1981). Responses of pontine units to skin temperature changes in the guinea-pig. J. Physiol.314, 189–194.

  8. Werner, J., Schingnitz, G. & Hensel, H. (1980). Central neuronal activity in warm- and cold-adapted rats. Pflügers Arch. Suppl.384, R 25.

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Hinckel, P., Schröder-Rosenstock, K. Central thermal adaptation of lower brain stem units in the guinea-pig. Pflugers Arch. 395, 344–346 (1982).

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Key words

  • Thermoregulation
  • cold adaptation
  • thermoafferent system
  • pontine single units
  • central thermal adaptation