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  • Transport Processes, Metabolism and Endocrinology; Kidney, Gastrointestinal Tract, and Exocrine Glands
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Central thermal adaptation of lower brain stem units in the guinea-pig

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Summary

Cold adaptive changes were found in single units responding to thermal skin stimulation. All units were located in the subcoeruleus region of the lower brain stem. In cold-adapted guinea-pigs (five weeks in ambient temperature of 4°C), the maximum activity of cold-responsive neurones was reduced markedly in comparison with that of cold-responsive neurones in animals adapted to room temperature (ca. 21°C). This decrease may be a neuronal correlate to long-term downward shifts of shivering threshold temperature known to occur within adaptation periods of several weeks in man, as well as in animals.

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References

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Hinckel, P., Schröder-Rosenstock, K. Central thermal adaptation of lower brain stem units in the guinea-pig. Pflugers Arch. 395, 344–346 (1982). https://doi.org/10.1007/BF00580800

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Key words

  • Thermoregulation
  • cold adaptation
  • thermoafferent system
  • pontine single units
  • central thermal adaptation