Chemistry of Natural Compounds

, Volume 18, Issue 4, pp 466–472 | Cite as

Synthetic analogs ofPeganum alkaloids. I. Synthesis of methoxy- and hydroxy-substituted deoxyvasicinones and deoxypeganines

  • A. Karimov
  • M. V. Telezhenetskaya
  • S. Yu. Yunusov
Article
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Abstract

6-Methoxy-, 7-methoxy-, and ′8-methoxydeoxyvasicinones have been synthesized by the reaction of substituted (3-methoxy-, 4-methoxy-, and 5-methoxy-) anthranilic acids with α-pyrrolidone. The demethylation of these compounds has given the corre-sponding hydroxy-substituted analogs of deoxyvasicinone, and the reduction of the products obtained with zinc in hydrochloric acid has given the hydroxy- and methoxy- analogs of deoxypeganine. 8-Hydrooxydeoxypeganine dimethyl-, ethyl-, and butylcarbamates have been obtained by the carbamoylation of 8-hydroxydeoxypeganine.

Keywords

Isatin Anthranilic Acid Mixed Melting Point Zinc Dust Songorine 

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • A. Karimov
  • M. V. Telezhenetskaya
  • S. Yu. Yunusov

There are no affiliations available

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