A number of analogs of natural isoflavones have been synthesized. The starting materials were 2,4-dihydroxydeoxybenzoins obtained under modified conditions of the Houben-Hoesch reaction. The yields of the isoflavones synthesized were 63–69%. All the analogs of natural flavones possess a pronounced hypolipidemic action.
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G. N. Dorofeenko, A. L. Shinkarenko, A. L. Kazakov, A. I. Pyshchev, and V. V. Mezheritskii, Khim. Prir. Soedin., 160 (1974).
A. L. Kazakov, Khim.-Farm. Zh., No. 1, 58 (1979).
A. L. Kazakov and S. F. Dzhumyrko, Rast. Res., No. 3, 344 (1979).
M. S. Luk'yanchikov, Khim. Prir. Soedin., 43 (1984).
A. L. Kazakov and N. I. Kokovkii-Shcherbak, “The prediction of the biological activities of isoflavones as functions of their structures with the aid of an additive model,” in: Abstracts of Lectures at the IIIrd All-Union Congress of Pharmacists of the USSR [in Russian], Kishinev (1980).
P. E. Spoerri and A. S. DuBois, Organic Reactions, Coll. Vol.5, 387–412 (1949).
Pyatigorsk Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 781–784, November–December, 1985.
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Luk'yanchikov, M.S., Khilya, V.P. & Kazakov, A.L. Synthesis of analogs of natural isoflavones from 2,4-dihydroxydeoxybenzoins. Chem Nat Compd 21, 740–743 (1985). https://doi.org/10.1007/BF00576209
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