Lethal no-differentiation and the development of the imaginal discs during the larval stage inDrosophilia

  • H. H. El Shatoury
Article
Received:

Summary

  1. 1.

    Lethal no-differentiation, symboll-nd, is characterised by the failure of some or all of the imaginal buds to continue differentiation during the larval third instar. This is due to abnormal proliferation of the imaginal disc mesoderm.

     
  2. 2.

    There is a well-defined sequence in the sensitivity of the different organs to the lethal effect, the legs being the most commonly affected, and the genital disc the least commonly.

     
  3. 3.

    The abnormal proliferation of the mesoderm is preceded by degenerative changes in the lymph glands.

     
  4. 4.

    The mechanism of differentiation of the imaginal buds is discussed and it is argued that the organisation of the imaginal organs is determined primarily by the mesoderm.

     
  5. 5.

    It is suggested that the proliferation of the imaginal bud mesoderm is normally inhibited by a “bud-differentiation hormone” secreted by the lymph glands. The requirements of the different imaginal discs from this postulated hormone were represented by a histogram, in fig. 14.

     

Keywords

Lymph Gland Developmental Biology Larval Stage Degenerative Change Lethal Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abreviations

AD

abdomen

DP

disc proper

EY

eye

HEX

melanised hexagons

HD

head

HT

halter

LG

legs

LGD

leg buds

MES

mesoderm

MP

mouth parts

PC

peripodial cavity

PM

peripodial membrane

RD

ruptured disc proper

SG

salivery glands

SP

spheroids

TH

thorax

WG

wings

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References

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Copyright information

© Springer-Verlag 1955

Authors and Affiliations

  • H. H. El Shatoury
    • 1
  1. 1.Institute of Animal GeneticsEdinburgh UniversityScotland

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