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The effects of bromodeoxyuridine and bromouracil on regeneration inHydra

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The effects on tentacle regeneration inHydra of two DNA-antimetabolites, bromouracil and bromodeoxyuridine, have been studied. Bromouracil inhibits tentacle regeneration inH. vulgaris andH. viridis; bromodeoxynridine inhibits tentacle regeneration inH. vulgaris but notH. viridis over the range of concentrations studied. Thus these two species appear to differ in their susceptibilities to these drugs, and the drugs may have different efficacies in this system.

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Goyns, M.H., Stanisstreet, M. The effects of bromodeoxyuridine and bromouracil on regeneration inHydra . W. Roux' Archiv f. Entwicklungsmechanik 175, 87–90 (1974). https://doi.org/10.1007/BF00574294

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  • Developmental Biology
  • Bromodeoxyuridine
  • Bromouracil
  • Tentacle Regeneration