Advertisement

Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Attempts to obtain a friend virus-induced ascites tumor free of the virus

  • 17 Accesses

  • 4 Citations

Summary

A line of NVP type Friend tumor cells which was considered not to produce Friend virus particles was obtained. Based on the fact that the biological nature of this line was identical to that of VP Friend tumor cells which continues to produce virus it was surmised that the existence of Friend virus particles itself is not an absolutely necessary condition for the maintenance or proliferation of Friend tumor.

Zusammenfassung

Eine Linie der Friend-Tumor-Zellen, die nicht die Friend-Virus-Partikel bilden (NVP-Typ), besitzen biologisch fast dieselbe Natur wie Friend-Tumor-Zellen, die die Viren bilden (VP-Typ). Die Existenz der Friend-Virus-Partikel sei also nicht unbedingt notwendig für das Wachstum des Friend-Tumors.

This is a preview of subscription content, log in to check access.

References

  1. Axelrad, A. A., andR. A. Steeres: Assay for Friend leukemia virus: Rapid quantitative method based on enumeration of macroscopic spleen foci in mice. Virology24, 513–518 (1964).

  2. Bernhard, W., andN. Granboulan: Morphology of oncogenic and non-oncogenic mouse viruses. A Ciba Foundation, 6–55. London: Churchill 1962.

  3. De Harven, E., andC. Friend: Further electronmicroscope studies of a mouse leukemia induced by cell-free filtrate. J. biophys. biochem. Cytol.7, 747–752 (1960).

  4. Fieldsteel, A. H., P. J. Dawson, andJ. Scholler: Virus-free Friend virus-induced tumor: In vitro and in vivo characteristics. J. Nat. Cancer. Inst.36, 71–81 (1966).

  5. Friend, C.: Immunological relationships of a filtrable agent causing a leukemia in adult mice. I. The neutralization of infectivity by specific antiserum. J. Exp. Med.109, 217–228 (1959).

  6. Hanafusa, H., T. Hanafusa, andH. Rubin: The defectiveness of Rous sarcoma virus. Proc. Nat. Acad. Sci. (Wash.)49, 572–580 (1963).

  7. Kasuga, T., andK. Oota: Pathological character, of Friend disease. Gann no Rinsyo8, 251–265 (1962).

  8. Kobayashi, H.: Immunopathologic studies on the Friend virus-induced ascitic tumor. Acta Path. Jap.16, 79–95 (1966).

  9. Kobayashi, H., T. Kodama, andK. Takeda: Electronmicroscopic studies of Friend tumor cell with special reference to the influence of Friend virus immunity of Friend tumor cell. Nature (submitted).

  10. Moloney, J.: Biological studies on a lymphoid-leukemia virus extracted from Sarcoma37. I. Origin and introductory investigation. J. Nat. Cancer Inst.24, 933–951 (1960).

  11. Moore, A.: Growth and persistence of Friend leukemia virus in tissue culture. J. nat. Cancer Inst.30, 885–895 (1963).

  12. Oboshi, S., K. Aoki, R. Sato, andT. Baba: Friend virus ascites sarcoma: a transplantable ascites tumor variant induced from Friend viral leukemia. Gann55, 73–82 (1964).

  13. Pluznik, K. H., andL. J. Sachs: Quantitation of a murine leukemia virus with a spleen colony assay. J. Nat. Cancer Inst.33, 535–546 (1964)

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kobayashi, H., Takeda, K., Kodama, T. et al. Attempts to obtain a friend virus-induced ascites tumor free of the virus. Z Krebs-forsch 69, 10–18 (1967). https://doi.org/10.1007/BF00571736

Download citation

Keywords

  • Public Health
  • Tumor Cell
  • Cancer Research
  • Virus Particle
  • Ascites Tumor