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Attempts to obtain a friend virus-induced ascites tumor free of the virus

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A line of NVP type Friend tumor cells which was considered not to produce Friend virus particles was obtained. Based on the fact that the biological nature of this line was identical to that of VP Friend tumor cells which continues to produce virus it was surmised that the existence of Friend virus particles itself is not an absolutely necessary condition for the maintenance or proliferation of Friend tumor.


Eine Linie der Friend-Tumor-Zellen, die nicht die Friend-Virus-Partikel bilden (NVP-Typ), besitzen biologisch fast dieselbe Natur wie Friend-Tumor-Zellen, die die Viren bilden (VP-Typ). Die Existenz der Friend-Virus-Partikel sei also nicht unbedingt notwendig für das Wachstum des Friend-Tumors.

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Kobayashi, H., Takeda, K., Kodama, T. et al. Attempts to obtain a friend virus-induced ascites tumor free of the virus. Z Krebs-forsch 69, 10–18 (1967).

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  • Public Health
  • Tumor Cell
  • Cancer Research
  • Virus Particle
  • Ascites Tumor