International Urogynecology Journal

, Volume 4, Issue 3, pp 146–151

A double-blind clinical trial of a β2-adrenergic agonist in stress incontinence

  • K. Yasuda
  • K. Kawabe
  • Y. Takimoto
  • A. Kondo
  • R. Takaki
  • K. Imabayashi
  • A. Toyoshima
  • A. Sato
  • J. Shimazaki
  • The Clenbuterol Clinical Research Group
Original Article

DOI: 10.1007/BF00571623

Cite this article as:
Yasuda, K., Kawabe, K., Takimoto, Y. et al. Int Urogynecol J (1993) 4: 146. doi:10.1007/BF00571623

Abstract

A multicenter double-blind placebo-controlled trial was performed on aβ2-adrenergic agonist, clenbuterol, in 165 women with stress incontinence. Clenbuterol remarkably improved the stress incontinence, and urodynamically the drug was found to increase the maximal urethral closure pressure. Some side effects were noted, but they were not serious. The results of this trial showed clenbuterol to be a promising drug for the treatment of stress incontinence.

Keywords

β2-agonist Clenbuterol Double-blind test Stress incontinence 

Copyright information

© The International Urogynecology Journal 1993

Authors and Affiliations

  • K. Yasuda
    • 1
  • K. Kawabe
    • 2
  • Y. Takimoto
    • 3
  • A. Kondo
    • 4
  • R. Takaki
    • 5
  • K. Imabayashi
    • 6
  • A. Toyoshima
    • 7
  • A. Sato
    • 8
  • J. Shimazaki
    • 1
  • The Clenbuterol Clinical Research Group
  1. 1.Department of UrologyChiba University School of MedicineJapan
  2. 2.Department of Urology, Branch Hospital, Faculty of MedicineUniversity of TokyoJapan
  3. 3.Department of UrologyNihon University School of Medicine, Surugadai HospitalJapan
  4. 4.Department of UrologyNagoya University School of MedicineJapan
  5. 5.Department of UrologyNiigata University School of MedicineJapan
  6. 6.Department of UrologyTohoku University School of MedicineJapan
  7. 7.Department of UrologyTeikyo University School of MedicineJapan
  8. 8.Department of PhysiologyTokyometropolitan Institute of GerontologyJapan
  9. 9.Department of Urology, School of MedicineChiba UniversityChiba CityJapan

Personalised recommendations