Diazepam significantly increased milk consumption in rats that had never been exposed to this food before but not in rats trained to drink milk. Diazepam failed to increase lever-pressing for food reward except when this behavior had been previously suppressed by the simultaneous administration of electric shock. These data suggest that diazepam does not alter appetite, but enhances the expression of motivation suppressed by instinct or training.
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Barnett, S. A.: Experiments on “neophobia” in wild and laboratory rats. Br. J. Phychol.49, 195–201 (1958)
Fratta, W., Mereu, G., Chessa, P., Paglietti, E., Gessa, G.: Benzodiazepine-induced voraciousness in cats and inhibition of amphetamine-anorexia. Life Sci.18, 1157–1166 (1976)
Geller, I., Seifter, J.: The effect of meprobamate, barbiturates,d-amphetamine and promazine on experimentally induced conflict in the rat. Psychopharmacologia (Berl.)1, 482–492 (1960)
Kirk, R. E.: Experimental design: procedures for the behavioral sciences. Belmont, Calif.: Brooke-Cole 1968
Poschel, B. P. H.: A simple and specific screen for benzodiazepinelike drugs. Psychopharmacologia (Berl.)19, 193–198 (1971)
Soubrié, P., Kulkarni, S., Simon, P., Boissier, J. R.: Effets des anxiolytiques sur la prise de nourriture de rats et de souris placés en situation nouvelle ou familière. Psychopharmacologia (Berl.)45, 203–210 (1975)
Tye, N. C., Nicholas, D. J., Morgan, M. J.: Chlordiazepoxide and preference for free food in rats. Pharmacol. Biochem. Behav.3, 1149–1151 (1975)
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Johnson, D.N. Effect of diazepam on food consumption in rats. Psychopharmacology 56, 111–112 (1978). https://doi.org/10.1007/BF00571417
- Food consumption