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Autoradiographic studies on glucose utilization in individual zone of the rat thymus

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Summary

Wistar rats were injected intraperitoneally with 2-(14C)deoxyglucose and their thymuses were processed for thaw-mount autoradiography after 5, 10 or 35 min. Highest levels of radioactivity were demonstrated in the thymic medulla (5-fold higher than in the cortex). Scanning of autoradiograms for regional differences in grain densities indicated particularly intense glucose utilization in the cortico-medullary zone. Differences in glucose utilization between individual thymic zones seem to reflect differences in cellular composition, i. e., ratio of stroma cells to thymocytes.

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Correspondence to J. B. Warchol.

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Dedicated to Professor Dr. T.H. Schiebler on the occasion of his 65th birthday

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Warchol, J.B., Pilgrim, C., Ginda, W.J. et al. Autoradiographic studies on glucose utilization in individual zone of the rat thymus. Histochemistry 88, 571–573 (1988). https://doi.org/10.1007/BF00570326

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Keywords

  • Public Health
  • Glucose
  • Stroma Cell
  • Regional Difference
  • Glucose Utilization