Chemistry of Natural Compounds

, Volume 7, Issue 3, pp 333–337 | Cite as

Investigations in the field of tetracyclines

LV. Synthesis of 4N-desmethyl-12a-deoxy-5a, 6-anhydrotetracyclines
  • L. N. Gladkova
  • A. I. Gurevich
  • M. G. Karapetyan
  • M. N. Kolosov
  • V. G. Korobko
Article
  • 16 Downloads

Summary

The synthesis of 4-N-desdimethyl- (IIa) and 4-N-desmethyl-12a-deoxy-5a,6-anhydrotetracycline (IIb) has been effected.

Keywords

Ethyl Ester Sodium Hydride Benzyl Bromide Saturated NaC1 Solution Diglyme 

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Literature cited

  1. 1.
    A. I. Gurevich, M. G. Karapetyan, M. N. Kolosov, V. G. Korobko, S. A. Popravko, and M. M. Shemyakin, Dokl. Akad. Nauk SSSR,174, 358 (1967); Tetrahedron Lett.,1967, 131.Google Scholar
  2. 2.
    A. I. Gurevich, M. G. Karapetyan, and M. N. Kolosov, Khim. Prirodn. Soedin.,2, 141 (1966);6, 247 (1970).Google Scholar
  3. 3.
    M. Schach von Wittenau, J. Org. Chem.,29, 2746 (1964).CrossRefGoogle Scholar
  4. 4.
    A. I. Gurevich, M. G. Karapetyan, M. N. Kolosov, V. G. Korobko, V. V. Onoprienko, and S. A. Popravko, Zh. Obshch. Khim.38, 50 (1968).Google Scholar
  5. 5.
    A. I. Gurevich, M. N. Kolosov, V. G. Korobko, and S. A. Popravko, Zh. Obshch. Khim.,38, 57 (1968).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1973

Authors and Affiliations

  • L. N. Gladkova
  • A. I. Gurevich
  • M. G. Karapetyan
  • M. N. Kolosov
  • V. G. Korobko

There are no affiliations available

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