Chemistry of Natural Compounds

, Volume 14, Issue 5, pp 518–523 | Cite as

Some reactions of α-hydroxymethylene- and α-dimethylaminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones

  • É. Oripov
  • L. M. Yun
  • Kh. M. Shakhidoyatov
  • Ch. Sh. Kadyrov
Article
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Summary

By the reaction of α-hydroxymethylene- and α-dimethylaminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones with acid anhydrides and primary and secondary amines, the corresponding α-acyloxymethylene- and α-mono(di)-substituted aminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones have been synthesized. The addition of hydrocyanic acid (from acetone cyanohydrin) to the double bond of the methylene group of the α-hydroxymethylene- and α-dimethylaminomethylene-2,3-trimethylene-3,4-dihydroquinazolin-4-ones has led to α-[cyano-(hydroxy)methyl1]- and α-[cyano(dimethylamino)methyl]-2,3-trimethylene-3,4-dihydroquinazolin-4-ones.

Keywords

Transferrin Cyano Dimethylamino Enamine Hydrocyanic Acid 

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • É. Oripov
  • L. M. Yun
  • Kh. M. Shakhidoyatov
  • Ch. Sh. Kadyrov

There are no affiliations available

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