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Neutron activation analysis of the peptides of thyroglobulin

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The peptides of thyroglobulin obtained by enzymatic hydrolysis with pronase and by two-dimensional paper chromatography have been investigated by neutron activation analysis in order to determine the micro amounts of iodine in each peptide. The greatest amount of iodine is present in the 2nd, 7th, 12th, 13th, 14th, and 15th peptides. The bulk of the iodine is present in the 14th and 15th peptides, which contain 17.7 and 34.3%, respectively, of the total iodine. There is a definite direct correlation between the concentrations of iodine in them.

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Moscow Scientific-Research X-Radiographic Institute, Ministry of Health of the RSFSR. Institute of Nuclear Physics, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 37–41, January–February, 1975.

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Pyzhova-Ioffe, I.K., Kryzhenkova, N.A. Neutron activation analysis of the peptides of thyroglobulin. Chem Nat Compd 11, 35–38 (1975).

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  • Peptide
  • Iodine
  • Neutron Activation Analysis
  • Tyrosine Residue
  • Thyroglobulin